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Editorials

Patching together a world view
Data sets encapsulating the behaviour of the Earth system are one of the greatest technological achievements of our age — and one of the most deserving of future investment.

Africa's academies
Robust scientific institutions won't be built in a day.

Shared genomes
Nature's publishers are expanding the licence for reuse of genome papers.

Research Highlights

Research highlights

Journal Club

Journal club
Sarah E. Hitchcock-DeGregori

News

Columbus begins voyage of discovery
Europe's space lab finally reaches the launch pad.
Geoff Brumfiel

UN talks only one part of the negotiations needed on climate
Parallel discussions have important role to play.
Jeff Tollefson

Solar power: California's latest gold rush
Green-energy companies are enjoying a boom in investment. But will they live up to expectation, asks Declan Butler.
Declan Butler

Model predicts structure of crystals
Software solves long-standing chemical frustration.
Katharine Sanderson

Sidelines
Scribbles on the margins of science.

Saudi–Italian biomedical institute gets go-ahead
Hospital and cancer-research centre will form part of Red Sea development.
Alison Abbott

Asia plans first cancer network
Regional initiative will coordinate data sharing and epidemiology.
David Cyranoski

Fund boost for German science
Coalition government ploughs cash into research.
Quirin Schiermeier

Safer way to make human stem-like cells revealed

Risk analysis for Boston lab slammed as 'shoddy'

AIDS worker's misconduct ban belatedly comes to light

European satellite system is back on the launch pad

Californian stem-cell directors to be investigated

Endangered species cling on as rulings are overturned

Correction

Clarification

Business

Smart networking
Theoreticians have combined their expertise to form a network to help other scientists design materials or understand biological pathways. Katharine Sanderson reports.
Katharine Sanderson

News Features

Earth Monitoring: The planetary panopticon
Technology will soon allow the world to be mapped in near-real time and at high resolution. Declan Butler investigates the potential for operational monitoring of the planet.

Earth Monitoring: Observing the ocean from within

Earth Observation: Not enough eyes on the prize
The capacity of the United States to monitor Earth's vital signs is being stymied by tight budgets and poor coordination. Alexandra Witze reports.

Earth Monitoring: The crucial measurement

Correspondence

Thought: a different perspective
Marc D. Hauser

Thought: book review has my ideas back to front
Steven Pinker

Chance to learn and teach in the developing world
Tim Caro & Monique Borgerhoff Mulder

Few women join ranks of Germany's academic élite
Laura Niven

Commentaries

Earth monitoring: Cinderella science
On-the-ground monitoring is unglamorous work, seldom rewarded by funding agencies or the science community. But we neglect it at our peril, warns Euan Nisbet.

Earth monitoring: Vigilance is not enough
Global surveillance is key to tracking potential pandemic viruses such as H5N1. But we need to share samples more rapidly, increase testing in endemic areas and track more than one virus, argues Walter Boyce.

Books and Arts

The ultimate Romantic adventure
Napoleon's invasion of the Middle East enhanced rather than diminished the world's intellectual heritage.
Andrew Robinson reviews Mirage: Napoleon's Scientists and the Unveiling of Egypt by Nina Burleigh

Size matters, sometimes
Steven Murawski reviews Body Size: The Structure and Function of Aquatic Ecosystems

The importance of nothing
Lawrence Rudnick reviews The Void by Frank Close

Earth observation: A fresh perspective
Jennifer Meyer reviews Earth From Space by Andrew K. Johnston and Star Maps: History, Artistry, and Cartography by Nick Kanas and Spies in the Sky by Pat Norris

History of medicine: Ageing of plastic surgery

Science in culture
Cartography and power have long gone hand in hand, as this pilgrimage plan illustrates.
Martin Kemp

Essay

Earth Monitoring: Whole Earth comes into focus
To understand how our planet uses energy, we must integrate genetic data from microbial studies with satellite views of our planet.
Stewart Brand

News and Views

Diabetes: Missing links
Researchers have now probably pinpointed all the genes in the MHC genomic region that are risk factors in type 1 diabetes. As the MHC is unusually rich in genes involved in immunity, this is truly exciting.
Bart O. Roep

Condensed-matter physics: Shear madness
Cooled to temperatures just above absolute zero, solid helium starts to behave very oddly. But its 'supersolid' behaviour might just be the result of imperfections that change the bulk properties of the crystal.
Alan T. Dorsey & David A. Huse

Relativity: Still special
Is special relativity a clapped-out classical theory, to be replaced by a shiny new quantum model as soon as possible? On the contrary, it would seem: the theory still has a youthful ability to surprise us.
Giovanni Amelino-Camelia

Cancer: Immune pact with the enemy
Progress comes from the latest investigations into a long-standing question in immunology — the role of the immune system in maintaining small, potentially cancerous lesions in a state of dormancy.
Cornelis J. M. Melief

50 & 100 Years Ago

Microbiology: Bilingual bacteria
Many bacteria use chemical signals to coordinate group behaviour. A signal that suppresses virulence has been identified in the bacterium that causes cholera, and could be a new therapeutic target.
Matthew R. Parsek

Palaeoclimate: Slush find
A coupled model of palaeoclimate and carbon cycling turns up the heat on the idea that Earth once became a giant snowball. It supports instead a milder 'slushball Earth' history — but piquant questions remain.
Alan J. Kaufman

Oceanography: Siberian salt in the cellar
Richard Webb

Obituary: Arthur Kornberg (1918–2007)
Passionate biochemist with a love for enzymes.
Tania A. Baker

News and Views Q&A

Sustainable technology: Green chemistry
Modern life depends on the petrochemical industry — most drugs, paints and plastics derive from oil. But current processes for making chemical products are not sustainable in terms of resources and environmental impact. Green chemistry aims to tackle this problem, and real progress is being made.
Martyn Poliakoff & Pete Licence

Brief Communications Arising

Effective global conservation strategies
Ana S. L. Rodrigues

Grenyer et al. reply
Richard Grenyer, C. David L. Orme, T. Jonathan Davies, Sarah F. Jackson, Richard G. Davies, Valerie A. Olson, Kate E. Jones, Kevin J. Gaston, Tim M. Blackburn, Gavin H. Thomas, Peter M. Bennett, Pamela C. Rasmussen, Tzung-Su Ding, John L. Gittleman & Ian P. F. Owens

Articles

Snowball Earth prevention by dissolved organic carbon remineralization
W. Richard Peltier, Yonggang Liu & John W. Crowley

Engraftment of connexin 43-expressing cells prevents post-infarct arrhythmia
Wilhelm Roell, Thorsten Lewalter, Philipp Sasse, Yvonne N. Tallini, Bum-Rak Choi, Martin Breitbach, Robert Doran, Ulrich M. Becher, Seong-Min Hwang, Toktam Bostani, Julia von Maltzahn, Andreas Hofmann, Shaun Reining, Britta Eiberger, Bethann Gabris, Alexander Pfeifer, Armin Welz, Klaus Willecke, Guy Salama, Jan W. Schrickel, Michael I. Kotlikoff & Bernd K. Fleischmann

Bv8 regulates myeloid-cell-dependent tumour angiogenesis
Farbod Shojaei, Xiumin Wu, Cuiling Zhong, Lanlan Yu, Xiao-Huan Liang, Jenny Yao, Dominique Blanchard, Carlos Bais, Franklin V. Peale, Nicholas van Bruggen, Calvin Ho, Jed Ross, Martha Tan, Richard A. D. Carano, Y. Gloria Meng & Napoleone Ferrara

The molecular architecture of cadherins in native epidermal desmosomes
Ashraf Al-Amoudi, Daniel Castaño Díez, Matthew J. Betts & Achilleas S. Frangakis

Intrinsic motions along an enzymatic reaction trajectory
Katherine A. Henzler-Wildman, Vu Thai, Ming Lei, Maria Ott, Magnus Wolf-Watz, Tim Fenn, Ed Pozharski, Mark A. Wilson, Gregory A. Petsko, Martin Karplus, Christian G. Hübner & Dorothee Kern

Letters

A stability limit for the atmospheres of giant extrasolar planets
Tommi T. Koskinen, Alan D. Aylward & Steve Miller

Cryptomare magmatism 4.35 Gyr ago recorded in lunar meteorite Kalahari 009
Kentaro Terada, Mahesh Anand, Anna K. Sokol, Addi Bischoff & Yuji Sano

Low-temperature shear modulus changes in solid 4He and connection to supersolidity
James Day & John Beamish

Controlling cavity reflectivity with a single quantum dot
Dirk Englund, Andrei Faraon, Ilya Fushman, Nick Stoltz, Pierre Petroff & Jelena Vukovi

Linear and nonlinear optical spectroscopy of a strongly coupled microdisk–quantum dot system
Kartik Srinivasan & Oskar Painter

A crystallizing dense magma ocean at the base of the Earth's mantle
S. Labrosse, J. W. Hernlund & N. Coltice

Host–parasite 'Red Queen' dynamics archived in pond sediment
Ellen Decaestecker, Sabrina Gaba, Joost A. M. Raeymaekers, Robby Stoks, Liesbeth Van Kerckhoven, Dieter Ebert & Luc De Meester

Methanotrophy below pH 1 by a new Verrucomicrobia species
Arjan Pol, Klaas Heijmans, Harry R. Harhangi, Dario Tedesco, Mike S. M. Jetten & Huub J. M. Op den Camp

Methane oxidation by an extremely acidophilic bacterium of the phylum Verrucomicrobia
Peter F. Dunfield, Anton Yuryev, Pavel Senin, Angela V. Smirnova, Matthew B. Stott, Shaobin Hou, Binh Ly, Jimmy H. Saw, Zhemin Zhou, Yan Ren, Jianmei Wang, Bruce W. Mountain, Michelle A. Crowe, Tina M. Weatherby, Paul L. E. Bodelier, Werner Liesack, Lu Feng, Lei Wang & Maqsudul Alam

The major Vibrio cholerae autoinducer and its role in virulence factor production
Douglas A. Higgins, Megan E. Pomianek, Christina M. Kraml, Ronald K. Taylor, Martin F. Semmelhack & Bonnie L. Bassler

Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A
Sergey Nejentsev, Joanna M. M. Howson, Neil M. Walker, Jeffrey Szeszko, Sarah F. Field, Helen E. Stevens, Pamela Reynolds, Matthew Hardy, Erna King, Jennifer Masters, John Hulme, Lisa M. Maier, Deborah Smyth, Rebecca Bailey, Jason D. Cooper, Gloria Ribas, R. Duncan Campbell, David G. Clayton, John A. Todd & The Wellcome Trust Case Control Consortium

Characterizing the cancer genome in lung adenocarcinoma
Barbara A. Weir, Michele S. Woo, Gad Getz, Sven Perner, Li Ding, Rameen Beroukhim, William M. Lin, Michael A. Province, Aldi Kraja, Laura A. Johnson, Kinjal Shah, Mitsuo Sato, Roman K. Thomas, Justine A. Barletta, Ingrid B. Borecki, Stephen Broderick, Andrew C. Chang, Derek Y. Chiang, Lucian R. Chirieac, Jeonghee Cho, Yoshitaka Fujii, Adi F. Gazdar, Thomas Giordano, Heidi Greulich, Megan Hanna, Bruce E. Johnson, Mark G. Kris, Alex Lash, Ling Lin, Neal Lindeman, Elaine R. Mardis, John D. McPherson, John D. Minna, Margaret B. Morgan, Mark Nadel, Mark B. Orringer, John R. Osborne, Brad Ozenberger, Alex H. Ramos, James Robinson, Jack A. Roth, Valerie Rusch, Hidefumi Sasaki, Frances Shepherd, Carrie Sougnez, Margaret R. Spitz, Ming-Sound Tsao, David Twomey, Roel G. W. Verhaak, George M. Weinstock, David A. Wheeler, Wendy Winckler, Akihiko Yoshizawa, Soyoung Yu, Maureen F. Zakowski, Qunyuan Zhang, David G. Beer, Ignacio I. Wistuba, Mark A. Watson, Levi A. Garraway, Marc Ladanyi, William D. Travis, William Pao, Mark A. Rubin, Stacey B. Gabriel, Richard A. Gibbs, Harold E. Varmus, Richard K. Wilson, Eric S. Lander & Matthew Meyerson

Identification of protein pheromones that promote aggressive behaviour
Pablo Chamero, Tobias F. Marton, Darren W. Logan, Kelly Flanagan, Jason R. Cruz, Alan Saghatelian, Benjamin F. Cravatt & Lisa Stowers

Adaptive immunity maintains occult cancer in an equilibrium state
Catherine M. Koebel, William Vermi, Jeremy B. Swann, Nadeen Zerafa, Scott J. Rodig, Lloyd J. Old, Mark J. Smyth & Robert D. Schreiber

The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA
Jafar Sharif, Masahiro Muto, Shin-ichiro Takebayashi, Isao Suetake, Akihiro Iwamatsu, Takaho A. Endo, Jun Shinga, Yoko Mizutani-Koseki, Tetsuro Toyoda, Kunihiro Okamura, Shoji Tajima, Kohzoh Mitsuya, Masaki Okano & Haruhiko Koseki

A hierarchy of timescales in protein dynamics is linked to enzyme catalysis
Katherine A. Henzler-Wildman, Ming Lei, Vu Thai, S. Jordan Kerns, Martin Karplus & Dorothee Kern

Naturejobs

Prospect
Prospects
Salaries for scientists and engineers remain healthy — but differ by field, sector and country.
Gene Russo

Career View
Jose Alonso, director, Sanford Underground Science and Engineering Laboratory, Homestake, South Dakota
Richard Myers leaves Stanford genome centre for Huntsville.
Virginia Gewin

How to handle drug withdrawal
Pfizer's move out of Ann Arbor, Michigan, has left a hole that local institutions are attempting to fill — with mixed success.
Paul Smaglik

A conference too soon
I like going to meetings. But I've got to bide my time and mind my budget.
Chris Rowan

Futures

Life, abundant and with simple joy
Found in translation.
Sarah K. Castle

 


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